The Small Assassins

Viruses, bacteria, and fungi. Nature’s triple threat.

The PBS Newshour covers critical research into a new generation of antibiotics. Boston’s home team includes the Broad (pronounced “Brode”) Institute, MIT, and Mass General Hospital. I have a niece who works in one of the labs at the Broad.

A significant factor in the rise of drug-resistant bacteria has been the overuse of antibiotics, especially in animals.

https://www.ewg.org/news-insights/news/2024/11/life-saving-antibiotics-jeopardy-growing-use-factory-farmed-animals

From Senior to Freshman

The two happiest years of my childhood were 5th and 6th grade. As a young adult, the two most significant years were my senior year of high school and my freshman year of college. I shall forever carry the chains I forged during that time in my life.

Elton John’s ‘Goodbye Yellow Brick Road’ album appeared in the middle of first semester, freshman year. Kath’s roommate bought it right away, and I’d listen to it in their dorm room on the cheapie stereo they had. When Elton was good, he was great.

Another vivid memory was seeing a preview showing of The Exorcist, before its Christmas release date. I wanted Kath to go with me, but she refused, because the movie was “of Satan.”

Laura’s roommate Mary wanted to see The Exorcist, and how well I remember her clinging to me during the movie. It featured Mike Oldfield’s ‘Tubular Bells’, which is also indelibly associated with freshman year.

Which Do You Prefer? This? Or This?

Through all of my eye troubles long ago, from a detached retina to cataract replacement lenses, I learned to switch “eye dominance.” My left eye is for “close up” sight. My right eye is corrected for distance vision. This works very well for me.

By mentally de-emphasizing the “distance vision” in my right eye, I can usually get by without reading glasses. Looking up across the room, my right eye takes the lead. This happens automatically, without a thought.

I wear glasses when driving, to bring my left eye up to 20/20. The lenses in my distance glasses are getting scratched, so I’m going to make an appointment to get a new pair.

The fun part of an eye exam is after the prescription is getting close to correct, when the optometrist quickly flips the lenses back and forth in the phoropter. The question may go from “Which looks better?” to “Which do you prefer?”

That’s what it’s all about concerning so many things in life — what’s better vs. personal preference. In economics, this leads to discussions of cost/benefit analysis and diminishing returns. So, let’s make some comparisons.

I have the first and second generations of the Tangzu Waner in-ear monitor plugged into the porch’s laptop PC. (One of them is plugged into a USB-C DAC/Amp adapter.)

TANGZU WAN’ER (for Wanderer?) SG 2 IEM with New Bee memory foam eartips

The most significant difference between the two products is how they fit. The Waner 2 is much worse in this regard, as I explain in my Amazon review.

https://amazon.com/gp/customer-reviews/RE391S18LDF8F?ref=pf_ov_at_pdctrvw_srp

Regarding the measured frequency response curves for the two products, they are very similar overall. Yet, as stated in the review, the W2 is significantly brighter sounding in the upper treble.

Which is better? Neither. Which do I prefer? Both. It depends on the music being played. Both products cost only $20, so there is no diminishing return on the price.

If you can stand it, I’ll have some more comparisons coming up, regarding images rather than sound. First, I’ll return to music listening.

The original Waner is better for Pop and Rock music, and the Waner 2 is my preferred pair for Classical music. Here are all nine of Schubert’s symphonies from the good folks at the Brilliant Classics label.

Play Money

All I can do is keep thinking, in equal measures of hope and despair, “Three more years … Three more years …”

US Secretary of Treasury Scott Bessent shows a proposed $250 bill featuring President Donald Trump during a press briefing in the Brady Briefing Room of the White House in Washington, DC. KENT NISHIMURA/AFP via Getty Images

Bessent and Hassett. What a pair. They both have the same obsequious, sh*t-eating grin.

On Fox News, Hassett was, as usual, boasting about how great the economy is, when he was asked why Americans aren’t feeling it — why the long-running Michigan index of consumer sentiment has hit its lowest level ever. He responded by claiming that the index “is being driven by Democrats who have Trump derangement syndrome.”

https://paulkrugman.substack.com/p/whos-deranged-exactly